Selected recent publications


Burren OS, Guo H, and Wallace C. VSEAMS: A pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes. Bioinformatics, in press.
arXiv:1404.4482, software.

Zanda M, Onengut-Gumuscu S, Walker N, Shtir C, Gallo D, Wallace C, Smyth D, Todd JA, Hurles ME, Plagnol V, and Rich SS. A genome-wide assessment of the role of untagged copy number variants in type 1 diabetes. PLoS Genet, 10:e1004367, 2014.

Giambartolomei C, Vukcevic D, Schadt EE, Franke L, Hingorani AD,
Wallace C, and Plagnol V. Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics. PLoS Genet, 10:e1004383, 2014.
doi, ukpmc, software, webtool.

Pontikos N, Smyth DJ, Schuilenburg H, Howson JMM, Walker NM, Burren OS, Guo H,
Onengut-Gumuscu S, Chen WM, Concannon P, Rich SS, Jayaraman J, Jiang W,
Traherne JA, Trowsdale J, Todd JA, and Wallace C. A hybrid qPCR/SNP array approach allows cost efficient assessment of
KIR gene copy numbers in large samples. BMC Genomics, 15:274, 2014.
doi, ukpmc

*Ferreira RC, *Guo H, Coulson RMR, Smyth DJ, Pekalski ML, Burren OS, Cutler AJ,
Doecke JD, Flint S, McKinney EF, Lyons PA, Smith KGC, Achenbach P, Beyerlein
A, Dunger DB, Wicker LS, *Todd JA, *Bonifacio E, *Wallace C, and
*Ziegler G. A type I interferon transcriptional signature precedes autoimmunity
in children genetically at-risk of type 1 diabetes. Diabetes, 2014.
doi, ukpmc


Wallace C. Statistical testing of shared genetic control for potentially related traits. Genet Epidemiol, 37:802-813, 2013.
arXiv:1301.5510, doi, software.


Cooper JD, Simmonds MJ, Walker NM, Burren O, Brand OJ, Guo H, Wallace C, Stevens H, Coleman G, Wellcome Trust Case Control Consortium, Franklyn JA, Todd JA, and Gough SCL. Seven newly identified loci for autoimmune thyroid disease. Hum Mol Genet, 21:5202–5208, 2012.
doi, ukpmc.

Yang X, Todd JA, Clayton D, and Wallace, C. Extra-binomial variation approach for analysis of pooled DNA sequencing data. Bioinformatics, 28:2898–2904, 2012.
doi, ukpmc.

Wallace C, Rotival M, Cooper JD, Rice CM, Yang JHM, McNeill M, Smyth DJ, Niblett D, Cambien F, CC, Tiret L, Todd JA, Clayton DG, and Blankenberg S. Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes. Hum Mol Genet, 21:2815–2824, 2012.
doi, ukpmc.

Davison, L, Wallace, C, Cooper JD, Cope NF, Wilson NK, Smyth DJ, Howson JMM, Saleh N, Al-Jeffery A, Angus KL, Stevens HE, Nutland S, Duley S, Coulson RMR, Walker NM, Burren OS, Rice CM, Cambien F, Zeller T, Munzel T, Lackner K, Blankenberg S, CC, Fraser P, Gottgens B, and Todd JA. Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene. Hum Mol Genet, 21:322–333, 2012.
doi, ukpmc.


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