Haldane’s Sieve: Olly Burren writes about our latest preprint on arXiv, a method for relating GWAS summary statistics to functionally defined gene sets which doesn’t require access to raw genotyping data.
This is what you expect a typical SNP to look like:
There are three clearly distinguishable clusters representing the three possible genotypes at that locus (TT, TC and CC).
But some SNPs look like this:
What is going on here?